Week 2 pits the Cincinnati Bengals against the Jacksonville Jaguars in a clash that could hinge on run-first balance and big-play ability. Cincinnati eyes a sharper defense and Burrow-led offense, while Jacksonville leans on Lawrence’s arm and Etienne’s workload to accelerate the attack. Expect a high-scoring affair, with McPherson providing late-game scoring opportunities for the Bengals if the game stays tight.

Fantasy angles center on Etienne and Brian Thomas Jr. for Jacksonville, Burrow and McPherson for Cincinnati, and the favorable matchups that could unlock turnover-driven points for Cincinnati’s defense. The game sets up for a strategic, back-and-forth battle where early scripts may dictate the ceiling for several role players.

Christian Kirk will miss a second straight Texans game with a hamstring, leaving Nico Collins, Xavier Hutchinson and Justin Watson to pace Monday night’s attack against Tampa Bay. Braxton Berrios is out too, and rookies Jayden Higgins and Jaylin Noel could see extra targets as Tank Dell’s 2025 absence looms large.

Weeks 3 vs Jacksonville could finally bring Kirk back, a reunion with his former team that would reshape Houston’s target share and lift the value of the top three receivers and the rookies stepping in now.

Panthers are 0-1 after a flat opener with Jacksonville; Cardinals are 1-0 after a win over New Orleans. The Week 2 clash in Glendale tests Carolina's young core and Arizona's fresh momentum, with Arizona favored by 6.5 and eager to push toward a 2-0 start.

Bryce Young must rebound and Carolina's defense must clamp down; Chuba Hubbard could push for more touches if Carolina trails, while Budda Baker's presence on defense and the Cardinals' late-game execution will be key fantasy pivots in this matchup.